Our Open Letter to the W.H.O. Changing minds will change the HIV epidemic. By signing and sharing the open letter, you’re helping to drive the global HIV update. The Open Letter We’re calling on the Director-General of the WHO, the politicians of the world, and its citizens: rename the human immunodeficiency virus.Three letters, H-I-V, carry a long history of stigma we can’t treat. So, let’s push past the stigma, let’s rename HIV, and finally end the Epidemic of the Mind.